Focus on Middle East respiratory syndrome coronavirus (MERS-CoV)
Identifieur interne : 000566 ( Main/Exploration ); précédent : 000565; suivant : 000567Focus on Middle East respiratory syndrome coronavirus (MERS-CoV)
Auteurs : A. Bleibtreu [France] ; M. Bertine [France] ; C. Bertin [France] ; N. Houhou-Fidouh [France] ; B. Visseaux [France]Source :
- Medecine et Maladies Infectieuses [ 0399-077X ] ; 2019.
Abstract
MERS-CoV was first detected in June 2012 in Saudi Arabia. On October 16, 2018, 2260 cases and 803 related deaths had been reported in 27 countries. Although this emerging virus seems unlikely to become endemic in humans, it is still present and has not disappeared rapidly in less than 2 years like the SARS coronavirus. In this review, we discuss the main findings about the origin, emergence and virological characteristics of this virus, as well as preventive measures, the typical clinical picture, and currently available therapeutic options.
Url:
DOI: 10.1016/j.medmal.2019.10.004
PubMed: 31727466
PubMed Central: 7125975
Affiliations:
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Bleibtreu</name><affiliation wicri:level="3"><nlm:aff id="aff0005">Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP–HP, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP–HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Bertine, M" sort="Bertine, M" uniqKey="Bertine M" first="M." last="Bertine">M. Bertine</name><affiliation wicri:level="3"><nlm:aff id="aff0010">Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Bertin, C" sort="Bertin, C" uniqKey="Bertin C" first="C." last="Bertin">C. Bertin</name><affiliation wicri:level="3"><nlm:aff id="aff0005">Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP–HP, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Service des maladies infectieuses et tropicales, hôpitaux universitaires Pitié-Salpêtrière Charles Foix, AP–HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Houhou Fidouh, N" sort="Houhou Fidouh, N" uniqKey="Houhou Fidouh N" first="N." last="Houhou-Fidouh">N. Houhou-Fidouh</name><affiliation wicri:level="3"><nlm:aff id="aff0010">Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Visseaux, B" sort="Visseaux, B" uniqKey="Visseaux B" first="B." last="Visseaux">B. Visseaux</name><affiliation wicri:level="3"><nlm:aff id="aff0010">Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Laboratoire de Virologie, IAME, UMR 1137, Hôpital Bichat, Sorbonne Paris Cité, Université Paris Diderot, AP–HP, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Medecine et Maladies Infectieuses</title><idno type="ISSN">0399-077X</idno><idno type="eISSN">1769-6690</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">MERS-CoV was first detected in June 2012 in Saudi Arabia.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">On October 16, 2018, 2260 cases and 803 related deaths had been reported in 27 countries.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Although this emerging virus seems unlikely to become endemic in humans, it is still present and has not disappeared rapidly in less than 2 years like the SARS coronavirus.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">In this review, we discuss the main findings about the origin, emergence and virological characteristics of this virus, as well as preventive measures, the typical clinical picture, and currently available therapeutic options.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. 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Wells</name></author><author><name sortKey="Sloan, M A" uniqKey="Sloan M">M.A. Sloan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Bleibtreu, A" sort="Bleibtreu, A" uniqKey="Bleibtreu A" first="A." last="Bleibtreu">A. Bleibtreu</name></region><name sortKey="Bertin, C" sort="Bertin, C" uniqKey="Bertin C" first="C." last="Bertin">C. Bertin</name><name sortKey="Bertine, M" sort="Bertine, M" uniqKey="Bertine M" first="M." last="Bertine">M. Bertine</name><name sortKey="Houhou Fidouh, N" sort="Houhou Fidouh, N" uniqKey="Houhou Fidouh N" first="N." last="Houhou-Fidouh">N. Houhou-Fidouh</name><name sortKey="Visseaux, B" sort="Visseaux, B" uniqKey="Visseaux B" first="B." last="Visseaux">B. 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